RapidWeaver has been around for a while, but I hadn't seen it until now. Quite a funny idea: essentially a GUI editor for websites, not just individual pages. There are pre-made templates for various purposes (blogs, photo albums, etc.) and integrated, specialized editors for these elements. With a plugin API to program your own page types. But absolutely not WYSIWYG, just an integrated preview.
The HTML source - this is now my second great homepage tonight - looks somewhat okay. At least more than just DIV tags are used. However, the strange HEAD with all the LINK tags does irritate me a bit. But the result is already usable.
The templates themselves are not as slick as those from Sandvox - they seem a bit homespun and somewhat clunky (e.g., the font selection in the body text on my example page looks a bit ugly - I can't quite pinpoint what bothers me, but the Sandvox page just looks better).
What I don't like: only FTP and .Mac for publishing. SFTP is really not entirely new; this should be supported. Otherwise, it is most comparable to my good old PyDS for me - specialized editors for each content type with automatic rendering to HTML and automatic uploading to the server.
Oh, and the program handles 39 images in a photo album without any disasters, doesn't consume the computer's memory and small children to achieve the result.